Laurent Meijer Selected Research

Cytidine

2/2016

Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1.

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Laurent Meijer Research Topics

Disease

45	Neoplasms (Cancer) 01/2023 - 04/2000
34	Alzheimer Disease (Alzheimer's Disease) 12/2023 - 04/2000
20	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 07/2002
12	Down Syndrome (Down's Syndrome) 12/2023 - 06/2011
6	Neuroblastoma 10/2012 - 07/2006
5	Cystic Fibrosis (Mucoviscidosis) 01/2022 - 01/2016
5	Virus Diseases (Viral Diseases) 01/2022 - 06/2003
5	Infections 01/2022 - 01/2010
5	Breast Neoplasms (Breast Cancer) 09/2014 - 04/2009
4	Leukemia 01/2022 - 07/2015
3	Inflammation (Inflammations) 01/2022 - 01/2016
3	Leishmaniasis 01/2016 - 10/2009
3	Osteosarcoma (Osteogenic Sarcoma) 03/2014 - 11/2006
3	Glomerulonephritis 09/2005 - 04/2000
2	Cognitive Dysfunction 01/2023 - 01/2018
2	Rheumatoid Arthritis 01/2022 - 01/2016
2	Pain (Aches) 01/2022 - 01/2016
2	Pituitary ACTH Hypersecretion 01/2022 - 01/2016
2	Tauopathies 06/2021 - 01/2019
2	Parkinson Disease (Parkinson's Disease) 06/2021 - 01/2020
2	Carcinoma (Carcinomatosis) 02/2016 - 09/2014
2	Neoplasm Metastasis (Metastasis) 10/2013 - 05/2011
1	Congenital Heart Defects (Congenital Heart Defect) 01/2024
1	Pheochromocytoma 01/2022
1	Human Influenza (Influenza) 06/2021
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 06/2021
1	Nervous System Diseases (Neurological Disorders) 06/2021
1	Autistic Disorder (Autism) 06/2021
1	CDKL5 deficiency disorder 06/2021
1	Glioblastoma (Glioblastoma Multiforme) 06/2021
1	Osteoarthritis 06/2021
1	Telomeric 22q13 Monosomy Syndrome 06/2021
1	Acute Megakaryoblastic Leukemia (Leukemia, Megakaryocytic) 06/2021
1	Dementia (Dementias) 06/2021
1	Pick Disease of the Brain (Pick's Disease) 06/2021
1	Pancreatic Neoplasms (Pancreatic Cancer) 06/2021
1	Salivary Gland Neoplasms (Salivary Gland Cancer) 05/2021
1	Closed Head Injuries 01/2019
1	Brain Concussion (Cerebral Concussion) 01/2019
1	Amyloid Plaque 01/2019
1	Trisomy (Trisomies) 01/2018
1	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2018
1	Cysts 01/2018
1	Lung Diseases (Lung Disease) 01/2017
1	Cystic Kidney Diseases (Cystic Kidney Disease) 01/2016

Drug/Important Bio-Agent (IBA)

26	Phosphotransferases (Kinase)IBA 01/2023 - 01/2003
20	RoscovitineIBA 01/2022 - 06/2003
16	Protein Kinases (Protein Kinase)IBA 01/2022 - 03/2007
16	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2018 - 07/2002
10	Dyrk KinasesIBA 01/2024 - 11/2012
6	Glycogen Synthase Kinase 3IBA 11/2012 - 01/2003
5	Proteins (Proteins, Gene)FDA Link 01/2024 - 01/2013
5	EnzymesIBA 01/2022 - 09/2002
5	Amyloid (Amyloid Fibrils)IBA 08/2019 - 01/2013
4	Cyclin EIBA 05/2021 - 04/2009
4	Cyclin BIBA 09/2013 - 01/2003
4	Glycogen Synthase (Synthase I)IBA 10/2009 - 07/2002
3	Messenger RNA (mRNA)IBA 06/2021 - 11/2006
3	Biomarkers (Surrogate Marker)IBA 05/2021 - 12/2013
3	Protein Kinase InhibitorsIBA 11/2020 - 09/2009
3	purineIBA 01/2020 - 09/2008
3	Tyrosine (L-Tyrosine)FDA Link 01/2019 - 01/2008
3	Peptides (Polypeptides)IBA 01/2018 - 12/2012
3	Casein Kinases (Casein Kinase)IBA 01/2018 - 11/2006
3	indirubinIBA 09/2014 - 09/2006
3	Casein Kinase I (Casein Kinase 1)IBA 01/2014 - 07/2007
3	Cyclin AIBA 09/2013 - 01/2003
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2024 - 02/2005
2	leucettamine BIBA 12/2023 - 10/2017
2	((5Z)5- (1,3- benzodioxol- 5- yl)methylene- 2- phenylamino- 3,5- dihydro- 4H- imidazol- 4- one)IBA 01/2018 - 03/2014
2	Ion Channels (Ion Channel)IBA 01/2017 - 01/2016
2	Type I DNA Topoisomerases (Topoisomerase I)IBA 09/2013 - 10/2010
2	RNA Precursors (Precursor, mRNA)IBA 01/2013 - 06/2011
2	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2012 - 10/2008
2	Protein Isoforms (Isoforms)IBA 05/2011 - 04/2009
2	MicroRNAs (MicroRNA)IBA 07/2010 - 01/2010
2	Retinoblastoma ProteinIBA 09/2008 - 09/2007
2	RNA Polymerase II (RNA Polymerase B)IBA 09/2008 - 09/2007
2	Therapeutic UsesIBA 06/2003 - 09/2002
1	Tricarboxylic AcidsIBA 01/2022
1	Succinate Dehydrogenase (Fumarate Reductase)IBA 01/2022
1	ChloridesIBA 01/2022
1	Succinic Acid (Succinate)IBA 01/2022
1	HomocysteineIBA 06/2021
1	ChromatinIBA 06/2021
1	Folic Acid (Vitamin M)FDA LinkGeneric 06/2021
1	Methionine (L-Methionine)FDA Link 06/2021
1	fipronilIBA 01/2020
1	salicylhydroxamic acid (SHAM)IBA 01/2019
1	CytokinesIBA 01/2019
1	Lithium ChlorideIBA 01/2019
1	Interleukin-12 (IL 12)IBA 01/2019
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2019
1	PhosphoproteinsIBA 01/2018
1	Synapsins (Synapsin I)IBA 01/2018
1	CytidineIBA 02/2016
1	dCTP pyrophosphataseIBA 02/2016

Therapy/Procedure

12	Therapeutics 05/2021 - 02/2005
3	Drug Therapy (Chemotherapy) 04/2012 - 04/2000
1	Intraperitoneal Injections 01/2019